Preclinical Research Services
Nuclear Precision. Zero Compromise.
From early-phase research and development to IND-enabling studies, Cadena Research offers a broad range of preclinical services to support your radiopharmaceutical development program.
We can support proof of concept studies, candidate selection, lead optimization, efficacy, PK/PD, safety, toxicology, dosimetry and imaging for various compound classes.
All preclinical programs will receive personalized attention and access to senior-level experts, and will be overseen by one of our world-class Project Managers to ensure end-to-end project timeline and milestone tracking. All our services are designed to keep your development and goals on track and to bring your drug to market faster.
We welcome you to submit your intended study design for a complimentary discussion and feasibility review
Our preclinical services:
In vitro studies
- IC50 screening
- Cell culture and target expression
- Target binding & binding affinity
- Cytotoxicity
- Target internalization
In vivo studies
- Efficacy (xenograft models)
- Safety and Toxicology
- Dosimetry
- Pharmacokinetics/ Pharmacodynamics
- Biodistribution
- CT, PET, SPECT, Ultrasound Imaging, quantification and modeling
Other services
- Analytical support
- Companion diagnostic development